RainSure OmniPlex dPx System
The OmniPlex dPx is a revolutionary single-vesicle multi-omics analysis system engineered for the simultaneous dual detection of proteins and nucleic acids at the individual nanoparticle level. Utilizing ultra-sensitive targeted quantification, it provides researchers with direct, counting to accelerate biomarker discovery, vaccine development, and biopharmaceutical quality control.
RainSure OmniPlex dPx System
This platform offers unparalleled capabilities for the simultaneous detection and quantification of proteins and nucleic acids in the most demanding biopharmaceutical characterization workflows.
Redefining Standards for Single-Vesicle Multi-Omics Analysis
The OmniPlex dPx is a revolutionary single-vesicle multi-omics analysis system designed for the simultaneous dual detection of proteins and nucleic acids at the individual particle level. The platform is ideal for AAV viral vector evaluation, LNP delivery system evaluation, exosome (EV) research, vaccine development, and in vivo monitoring of CAR-T therapies. Whether determining the full-to-empty capsid ratio, quantifying packaging efficiency, or analyzing surface markers and nucleic acid loads in individual vesicles, the OmniPlex dPx transforms complex multiparameter analysis into a streamlined and highly reliable workflow.
Key Features & Capabilities:
- Simultaneous Multi-Omics Analysis: Synchronously acquires protein and nucleic acid profiles within a single capsid to provide deep analytical insights.
- Femtomolar Sensitivity: Achieves femtomolar-level absolute quantification to detect rare biomarkers in complex or unpurified matrices.
- Minimal Sample Requirement: Operates efficiently with sample volumes as low as 1 microliter, preserving precious clinical specimens.
- Precise Co-localization: Delivers robust evidence for the co-expression of surface markers and internal payloads on individual particles.
Core Applications:
- AAV Viral Vector Assessment: Provides quantitative analysis of empty, partial, and full capsids alongside genomic integrity and absolute titer measurement.
- LNP Delivery System Evaluation: Determines nucleic acid copy numbers per particle, monitors structural stability, and evaluates encapsulation efficiency.
- Exosome (EV) Research: Resolves vesicle heterogeneity, characterizes distinct subpopulations, and facilitates the transition from basic discovery to industrial quality control.
- Vaccine R&D and QC: Quantifies effective assembly components and validates lot consistency for viral vector, VLP, and mRNA vaccines.
- In vivo CAR-T Therapy Monitoring: Simultaneously detects CAR-transgene nucleic acids and surface protein markers at the single-particle level, enabling real-time assessment of viral vector integrity, transduction efficiency, and CAR-T cell-derived extracellular vesicle profiles throughout the course of therapy.